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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
U2AF2
All Species:
8.48
Human Site:
S53
Identified Species:
16.97
UniProt:
P26368
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P26368
NP_001012496.1
475
53501
S53
R
R
N
R
D
Q
R
S
A
S
R
D
R
R
R
Chimpanzee
Pan troglodytes
XP_530073
713
78555
N170
P
K
H
G
L
E
L
N
P
R
R
G
P
R
A
Rhesus Macaque
Macaca mulatta
XP_001091568
467
51268
G49
P
A
S
S
V
F
S
G
S
Q
L
L
L
S
I
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P26369
475
53499
S53
R
R
N
R
D
Q
R
S
A
S
R
D
R
R
R
Rat
Rattus norvegicus
Q63285
419
46487
G32
V
Q
S
R
L
G
S
G
S
S
A
S
V
Y
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080595
456
51328
Q51
K
E
R
R
A
R
E
Q
R
S
G
S
R
D
R
Zebra Danio
Brachydanio rerio
NP_991252
475
53612
R56
R
E
R
R
S
R
E
R
R
G
D
S
K
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24562
416
46636
D29
R
H
R
E
R
S
R
D
R
R
H
H
R
N
S
Honey Bee
Apis mellifera
XP_623055
432
48801
R42
R
R
K
R
S
R
S
R
S
K
D
R
R
D
R
Nematode Worm
Caenorhab. elegans
P90978
496
55412
G88
G
E
R
R
G
G
G
G
G
G
D
R
D
R
S
Sea Urchin
Strong. purpuratus
XP_001189425
444
50005
S45
K
S
T
G
R
S
R
S
G
S
R
D
R
D
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L716
589
66297
S159
R
S
R
S
R
S
R
S
E
R
R
S
R
S
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.4
87.5
N.A.
N.A.
99.7
20
N.A.
N.A.
N.A.
92
86.3
N.A.
66.7
66.7
51.4
62.9
Protein Similarity:
100
57.2
89.2
N.A.
N.A.
99.7
37.6
N.A.
N.A.
N.A.
94.7
92.2
N.A.
77
77.8
62.5
75.5
P-Site Identity:
100
13.3
0
N.A.
N.A.
100
20
N.A.
N.A.
N.A.
26.6
20
N.A.
20
33.3
13.3
46.6
P-Site Similarity:
100
40
13.3
N.A.
N.A.
100
40
N.A.
N.A.
N.A.
40
33.3
N.A.
20
46.6
13.3
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
9
0
0
0
17
0
9
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
17
0
0
9
0
0
25
25
9
25
0
% D
% Glu:
0
25
0
9
0
9
17
0
9
0
0
0
0
9
9
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
17
9
17
9
25
17
17
9
9
0
0
0
% G
% His:
0
9
9
0
0
0
0
0
0
0
9
9
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% I
% Lys:
17
9
9
0
0
0
0
0
0
9
0
0
9
0
0
% K
% Leu:
0
0
0
0
17
0
9
0
0
0
9
9
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
17
0
0
0
0
9
0
0
0
0
0
9
0
% N
% Pro:
17
0
0
0
0
0
0
0
9
0
0
0
9
0
0
% P
% Gln:
0
9
0
0
0
17
0
9
0
9
0
0
0
0
0
% Q
% Arg:
50
25
42
59
25
25
42
17
25
25
42
17
59
34
59
% R
% Ser:
0
17
17
17
17
25
25
34
25
42
0
34
0
17
17
% S
% Thr:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
9
0
0
0
9
0
0
0
0
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _